Immune reactions after modern lamellar (DALK, DSAEK, DMEK) versus conventional penetrating corneal transplantation

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343 The emergence of endothelial keratoplasty (EK) represents the beginning of a new era in the treatment of corneal endothelial disorders which continues to evolve. Fifteen years ago we were performing penetrating keratoplasty for Fuchs’ dystrophy and bullous keratopathy but nowadays we are performing selective replacement of the diseased endothelial layer. In recent years two techniques of EK...

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Glaucoma risks in advanced corneal surgery.

Penetrating corneal transplant (PKP) surgery has been performed for centuries as the procedure of choice to restore vision in cases of advanced corneal disease. However, the last two decades have seen the introduction of lamellar corneal surgery (deep anterior lamellar keratoplasty, DALK; Descemet stripping-automated endothelial keratoplasty, DSAEK; and Descemet membrane endothelial keratoplast...

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[Corneal transplantation in keratoconus: penetrating keratoplasty versus deep anterior lamellar keratoplasty with Melles technique].

OBJECTIVES To evaluate the effectiveness of deep anterior lamellar keratoplasty (DALK) using Melles technique (technique B) in patients with advanced keratoconus versus a classic technique, penetrating keratoplasty (technique A). METHODOLOGY Retrospective descriptive comparative study between technique A and technique B in homogeneous groups. RESULTS Best corrected visual acuity (Snellen te...

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Graft Biomechanics Following Three Corneal Transplantation Techniques

PURPOSE To compare corneal biomechanical properties following three different transplantation techniques, including Descemet stripping automated endothelial keratoplasty (DSAEK), deep anterior lamellar keratoplasty (DALK) and penetrating keratoplasty (PK) in comparison to normal eyes. METHODS This cross-sectional comparative study included 118 eyes: 17 eyes of 17 patients received DSAEK, 23 e...

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Corneal Regeneration by Deep Anterior Lamellar Keratoplasty (DALK) Using Decellularized Corneal Matrix

The purpose of this study is to demonstrate the feasibility of DALK using a decellularized corneal matrix obtained by HHP methodology. Porcine corneas were hydrostatically pressurized at 980 MPa at 10°C for 10 minutes to destroy the cells, followed by washing with EGM-2 medium to remove the cell debris. The HHP-treated corneas were stained with H-E to assess the efficacy of decellularization. T...

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ژورنال

عنوان ژورنال: Progress in Retinal and Eye Research

سال: 2019

ISSN: 1350-9462

DOI: 10.1016/j.preteyeres.2019.07.001